LncRNAs can regulate cancer cell migration by targeting Rho/ROCK signaling and include metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), actin filament associated protein 1 antisense RNA1 (AFAP1-AS1), and maternally expressed 3 (MEG3) [7, 107, 108]. This evidence concerns the gene RHO and cancer.