Ten patients suffered from congenital ichthyosis, seven of them having lamellar ichthyosis (Ichthyn: n 4, CYP4F22: n 1, TGM1: n 1, ongoing analysis: n 1) and three cases of congenital ichthyosiform erythroderma (two patients who carried ABCA12 mutations, and one who had no identified mutation). Here, CYP4F22 is linked to inherited ichthyosis.