In Cox regression, CTSK protein expression of tumor and stromal cells was dichotomized into low versus high based on the previously reported cut-off value, demonstrating a significantly worse DSS in OSCC subjects with increased CTSK protein expression (tumor: HR = 2.79, CI 1.02–7.64, p = 0.045 and stroma: HR = 2.40, CI 1.05–5.50, p = 0.038; Table 4). The gene discussed is CTSK; the disease is neoplasm.