In contrast, FGFR3–TACC3 is an inframe activating kinase fusion found in multiple cancer types, including glioblastoma multiforme (GBM) (Lasorella et al., 2017; Singh et al., 2012) and urothelial bladder carcinomas (BLCA) (Cancer Genome Atlas Research Network, 2014). Here, TACC3 is linked to glioblastoma.