S100A12 and digestive system neoplasm: Moreover, we observed the upregulation of other genes like CD177 Molecule (CD177), Phospholipid Scramblase 1 (PLSCR1), Secretory Leukocyte Peptidase Inhibitor (SLPI), S100 Calcium Binding Protein A12 (S100A12) and Integrin Beta 3 (ITGB3), all of them related to the development of different gastrointestinal tumors [61–66].