The extracellular chaperone clusterin is highly expressed in systemic ALCL, showing a characteristic Golgi staining pattern; however, clusterin reactivity has also been shown in a subset of diffuse large B-cell lymphomas (DLBCL), and in cases of PTCL-NOS and CHL [56]. Here, CLU is linked to mature T-cell and NK-cell non-Hodgkin lymphoma.