Identification of a potential biomarker for mesothelioma is another subject of current research.10 11 Soluble mesothelin-related peptide (mesothelin) has the greatest sensitivity and specificity in the diagnosis of mesothelioma compared with a number of other markers such as fibulin-3, osteopontin and megakaryocyte potentiating factor.12–14 Despite studies demonstrating an elevated mesothelin level at presentation of patients with MPM, its role in the diagnostic arena is yet to be established. Here, MSLN is linked to mesothelioma.