SRCAP and colorectal carcinoma: PIE1 is the ATPase of the SWR1 CRC that comprises other non-catalytic subunits such as ARP6, SWC6, SEF (Noh and Amasino, 2003; Deal, 2005; March-Diaz et al., 2006; Martin-Trillo, 2006; Lázaro et al., 2008).