PAEP and myalgic encephalomeyelitis/chronic fatigue syndrome: The most remarkable observation in this case–control study was that, as a group, the present CFS patients exhibited lower FT3, TT4, TT3, %TT3, SPINA-GD, SPINA-GT, T3/T4 ratios, lower protein binding of thyroid hormones, and 24-h urinary iodine excretion, together with higher %rT3.