CDKL3 and anaplastic large cell lymphoma: Previous studies have revealed that overexpression of CDKL3 was present in the invation anaplastic large cell lymphoma, and up-regulation of CDKL3 was reported to enhance cell proliferation of various mammalian cell lines, promote the transition from G0/G1 stage to S stage and accelerate cells enter the DNA synthesis stage phase (Thompson et al., 2005; Jaluria et al., 2007).