Recently, a role of Kir channels was reported in autism spectrum disorders (ASDs) due to the identification of two mutations (p.Arg18Gln and p.Val84Met) in the hKCNJ10 gene coding for the Kir4.1 subunit as well as one mutation in the KCNJ2 gene (p.Lys346Thr) coding the Kir2.1 subunit (Sicca et al., 2011). This evidence concerns the gene KCNJ10 and autism spectrum disorder.