IL4 and cancer: For example, IL-2:αIL-2 and IL-7:αIL-7 potentiate cellular immunity against cancer by enhancing activation of the IL-2 or IL-7 receptor α chain (IL-2αR or IL-7αR)44, whereas immunocomplexes consisting of IL-4 and a neutralizing mAb against IL-4 (αIL-4, clone 11B11) showed increased activity at the IL-4α receptor and protection against parasites45.