ABCB1 and ovarian carcinoma: Similarly, the doxorubicin-resistant, ABCB1-expressing A2780ADR ovarian cancer cell line exhibited only 4% of the doxorubicin uptake of parental A2780 cells and treatment of A2780ADR cells with β-cholanic acid (at 200 μM) also had no effect on their ability to accumulate doxorubicin.