VEGFA and neoplasm: As a biologic drug designed to target a single protein, bevacizumab may not conform well to a drug repositioning approach focusing on genome-wide expression differences, and our 80-tumor meta-analysis reveals that VEGF-A is not significantly upregulated in VSs when compared to GAN controls (Bonferroni-corrected meta-analytic p = 1; Supplementary Data File S1).