Actually, the gene maps to a locus of dilated cardiomyopathy (CMD1E/OMIM 601154), a disorder characterised by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia, eventually causing premature death that also harbours another gene encoding a cardiac muscle Na+ channel (SCN5A/HH1). Here, SCN5A is linked to dilated cardiomyopathy 1E.