GPT and malaria: The pathology results from the mice treated with the ethanolic extract of P. latifolia were the following: parasitic hepatitis characterized by hyperplasia, vacuolar degeneration, karyomegaly, and with presence of malaria pigment in the liver; mild acute congestive splenitis characterized by congestion with the presence of malaria pigment in the spleen; mild renal congestion characterized by vacuolar degeneration with presence of malarial pigment in the kidney; and finally, alterations in the liver enzymes alanine transaminase (ALT) and aspartate transaminase (AST) were observed.