The same transcription factor GATA3 also acts in type 2 innate lymphoid cells (ILC2 cells) and leads to a production of a similar, even though not identical cytokine pattern, including IL-5, IL-13 and, to a lesser extent, IL-4 [12–14], which might mediate airway eosinophilia in nonallergic asthma and COPD [15]. The gene discussed is IL5; the disease is chronic obstructive pulmonary disease.