BDNF and cancer: Distinct clusters stood out and showed significantenrichment with p values below 0.05 and qvalues below 0.10 (Fig. 2c).Melanogenesis and pathways in cancer, inflammation, nuclear factorkappa-light-chain-enhancer of activated B cells (NFκB) and signaltransducer and activator of transcription (STAT) signaling, metabolic pathwaysincluding alanine, tyrosine, valine, leucine, inositol, one-carbon metabolism,cell-adhesion molecules, neurotrophin signaling were over-represented in theupregulated dataset.