Chin et al. further showed the role of the α4β1 integrin and VCAM-1 on leukocyte trafficking in the airways of mice with OVA-induced asthma treated with anti-α4 integrin antibodies (PS/2, Rl-2) and anti-VCAM-1 monoclonal MoAb (M/K-2.7) [77]. Here, VCAM1 is linked to asthma.