Finally, this promoter region also contains recognition sequences for the transcriptional repressors CTIP2/Bcl11b, implicated in the developmental process and carcinogenesis, and the T-box transcription factor TBX3, which is involved in the tissue patterning and differentiation during embryonic development and is up-regulated in a plethora of cancers [80]. The gene discussed is BCL11B; the disease is cancer.