CD274 and gastric cancer: According to the histotype-based prognostic classification [14], 28/31 (90%) PD-L1+ cases were high lymphoid response (HLR) GCs, 2 were ordinary cohesive (one MSI GC with a moderate lymphoid reaction, the other a MSS/EBV− GC with only one tumor area rich in lymphocytes) and one was an anaplastic MSI GC with a moderate number of TILs.