In a recent paper, Mimura and colleagues [21] demonstrated a significantly increased PD-L1 expression, mainly via the JAK-STAT pathway, in gastric cancer cell lines treated with IFN-γ and a significant positive correlation between PD-L1 expression on tumor cells and high levels of stromal CD8+ T cells and tumor IFN-γ. The gene discussed is CD8A; the disease is neoplasm.