Since the decrease of the Muc5b expression is predicted to create an environment that promotes eosinophil survival [59] and, furthermore, the reduced Muc5b expression is a feature of severe (Th2-high) asthma [62], the P90-induced reduction of Muc5b mRNA levels also potentially indicates the worsening of allergic airway inflammation. Here, MUC5B is linked to asthma.