Although the antioxidant enzyme Gpx-3 had a decreased mRNA level after the OVA challenge, neither P90 nor the PAH-containing CBNP (P90-BaP, P90-9NA, or AS-PAH) induced the mRNA expression of cytokines or chemokines in the tracheal epithelial cells. The gene discussed is GPX3; the disease is pulmonary arterial hypertension.