Recently, another FoxO family member, FoxO6 was found to play a similar role as FoxO1 in regulating gluconeogenesis, as increased FoxO6 activity in the liver promoted gluconeogenesis and increased fasting blood glucose levels, whereas FoxO6 deletion in the liver reduced gluconeogenesis, resulting in fasting hypoglycemia. The gene discussed is FOXO6; the disease is Hypoglycemia.