Quantose MQ consisting of insulin, α-hydroxybutyrate, linoleoylglycerophosphocholine, and oleate correlated well with insulin-stimulated glucose disposal in the ACT NOW clinical study.(20) α-Hydroxybutyrate, linoleoylglycerophosphocholine, and oleic acid were useful biomarkers for identifying subjects with IGT independent of age, sex, BMI and fasting glucose without the need for the OGTT in a clinical study of European subjects without diabetes.(21) However, these biomarkers are low-molecular weight compounds that were detected using expensive instrumentation, namely HPLC-MS/MS. This evidence concerns the gene INS and diabetes mellitus.