ZNF471 and gastric cancer: Bisulfite genomic sequencing (BGS) results indicate that all the gastric cancer cell lines but MKN1 demonstrated hypermethylation at CpG sites in ZNF471 promoter region, whereas very low methylation was found in GES1 and normal gastric samples (Fig. 1b, c), consistent with ZNF471 expression in cell lines and gastric tissues.