TGFB1 and neoplasm: Importantly, the tumor size of nude mice transplanted with stably transfected pHBV4.1-HBs(sW172*) L02 cells were significantly smaller in TGF-β1 treatment group than in the PBS group (2.33±0.79 cm3 vs.4.45±1.03 cm3, P = 0.017) (Fig. 4).