MTOR and depressive symptom measurement: Simultaneously, accumulating evidence has shown that A-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor and subsequent mammalian target of rapamycin (mTOR) signaling way is responsible for the induction and maintenance of synaptic plasticity and may contribution to the synaptic alteration underlying depression [4, 5].