We also found a strong Tenascin-C immunoreactivity in the two Clival GCT biopsies, indicative of an aggressive tumour with a tendency to recur in situ, as this extracellular glycoprotein is highly expressed in the microenvironment of most solid tumours to promote migration and epithelial-mesenchymal transition [74]. The gene discussed is TNC; the disease is granular cell tumor.