STAT3 rs1053005 has been shown to be associated with ankylosing spondylitis and autoimmune thyroid disease in Han Chinese population [19, 20], to affect the risk of obesity and hypertriglyceridemia in Chinese Han population and French [21, 22], and to contribute to anti-tuberculosis drug-induced hepatitis (ATDH) susceptibility in Chinese Han population [23]. Here, STAT3 is linked to hepatitis A virus infection.