These include MMP8, a metallopeptidase that contributes to extracellular matrix remodeling, NAALAD2, a peptidase that hydrolyses N-acetyl-aspartyl glutamate and glutamate and a marker of prostatic carcinomas, and ACVRL1, a receptor for TGF-β family of ligands. Here, LAP3 is linked to prostate carcinoma.