found that lipokines that disrupt lipid metabolism and increase lipolysis, such as interleukin (IL)‐6, adiponectin, tumor necrosis factor alpha, and IL‐10, are upregulated in the plasma of cancer patients with cachexia; lipokine mRNA is also upregulated in patients’ subcutaneous tissues 44. The gene discussed is ADIPOQ; the disease is Cachexia.