Among these targets, 17 genes (NCAPG, SGOL1, RRM2, ESCO2, ZNF695, CDK1, NEK2, FANCI, FAM64A, ZWINT, PIGL, KIF11, MCM4, BRCA1, CDKN3, GRIA2, and MKI67) were involved in PCa pathogenesis, high expression of these genes were significantly associated with disease‐free survival rate (Figs 2B, 3). Here, ESCO2 is linked to posterior cortical atrophy.