DISC1 and major depressive disorder: Some of the important genetic variants associated with MDD that could be affected by shiftwork are APOE, SLC6A4, ACE, GNB3, HS6ST3, HTR1A, LHFPL2, PDE11A, DISC1, MAOA, SLC6A3 (DAT1), SLC25A21, VGLL4 BDNF, P2RX7, TPH2, PDE9A, and GRIK3 [95, 100].