APC and neoplasm: As we have previously demonstrated that epithelial loss of Mbd2 alone is capable of intestinal tumour suppression (Figure 1), it is of note that the Apc+/minMbd2−/−Ifng−/− mice (N = 6) displayed a small but significant increase in nuclear β‐catenin‐positive lesions (p = 0.03; average 2.6), indicating that in the absence of Ifng a small number of lesions can escape the tumour resistance conferred by epithelial Mbd2 loss.