Before investigating the effects of adiponectin on human epithelial ovarian cancer cells, we examined the expression of adiponectin and its receptors in epithelial ovarian cancer cell lines (OVCAR-3, SKOV-3, and Caov-3) and compared the mRNA levels with those in the granulosa tumor cell line (COV434). The gene discussed is ADIPOQ; the disease is ovarian carcinoma.