However, when protein phosphatase PP1 was expressed in the TLR4 overexpressing liver cancer stem cells, excessive TLR4 could significantly not alter the activity of telomerase (6.25 ± 1.37 vs 5.71 ± 1.91, P = .134 > 0.05) (Figure S8C). The gene discussed is TLR4; the disease is liver cancer.