Moreover, the phosphorylation levels of IRS2 (p‐IRS2/IRS2, at Ser731), AKT (at Ser473) and GSK3β (p‐GSK3β/GSK3β, at Ser9) were significantly decreased in cows with NASH (Figure 1G and H). Here, AKT1 is linked to metabolic dysfunction-associated steatohepatitis.