MT-CO1 and metabolic dysfunction-associated steatohepatitis: Pirez‐Cameras et al demonstrated that activities of OXPHOS complexes (COI‐V) were markedly decreased in the livers of patients with NASH.36 Koliaki et al found that the protein levels of COI, III, IV and V were lower in patients with NASH than in controls after correcting for mitochondrial content.21 In our study, we found that the hepatic protein levels of COI‐V showed a decreasing trend, and COI and III were significantly lower in patients with NASH than in controls.