NFKB1 and neoplasm: NF-κB targets that play an important role in cancer progression are those involved in epithelial-to-mesenchymal cell transition (EMT), such as Snail, Twist, matrix metalloproteinases (MMPs) and cell adhesion molecules that promote metastasis, and pro-angiogenic genes such as Vascular Endothelial Growth Factor (VEGF), stimulating tumour neovascularization [8,48,98,99,100].