MMP7 and myeloid sarcoma: MMP7 is the smallest MMP, and is particularly upregulated upon neuroinflammation in microglia/macrophages, that is in active demyelinating MS lesions, and in EAE, an animal model of MS (Anthony et al., 1997; Clements et al., 1997; Cossins et al., 1997; Kieseier et al., 1998; Lindberg et al., 2001).