GPT and liver disorder: The guidelines of American Association for the Study of Liver Diseases (AASLD) and Asian Pacific Association for the Study of the Liver for the management of CHB recommend antiviral treatment when ALT levels are two times the upper limit of normal (ULN), and monitoring or performing liver biopsy (especially for patients > 40 years) to assess if significant histologic disease is present when ALT levels are less than two times the upper limit of normal (ULN) [3, 4].