Interestingly, TFEB siRNA- and pEGFP-N1-TFEB-transfected A549 cells prolonged the significant reduction and increase of the A. baumannii persistence inside A549 cells during 8 h of bacterial infection by 2.95 and 1.17 log CFU/ml compared with control cells, respectively (Fig. 2E). The gene discussed is TFEB; the disease is bacterial infectious disease.