In agreement with previous reports (Serio et al., 2003), at 1-week post-infection non-adrenergic, non-cholinergic evoked relaxation in explants of ileum was abolished by the NOS inhibitor Nω-Nitro-L-arginine methyl ester hydrochloride (L-NAME), indicating its nitrergic origin (Figure 3E). The gene discussed is NOS2; the disease is infection.