MiR-150-5p functions as a tumor promoter in reducing chemosensitivity and promoting invasiveness of muscle-invasive bladder cancer cells lines by targeting PDCD4 [20], while miR-222-3p overexpression in bladder cancer tissues is associated with poor prognosis possibly via suppression of p27Kip1 [21]. This evidence concerns the gene CDKN1B and neoplasm.