BIRC5 and Bloom syndrome: Compared with the BLM group, the mRNA expression levels of survivin and VEGF in BLM + WYHZTL-H and BLM + XAV-939 group were downregulated (all P < 0.01), while BLM + WYHZTL-L and BLM + WYHZTL-M group didn’t significantly change (P > 0.05) (Fig. 2i).