Four hundred sixty-seven episodes of CBG along with the corresponding swipe FSL readings (average of 4.3 swipes per day) were available from the 11 (7 M) patients with diffuse CHI aged (0.5–5 years), 6 of them were negative mutations for in ABCC8, KCNJ11, GLUD1, GCK, HADH, HNF4A, INSR, HNF1A. This evidence concerns the gene GCK and congenital isolated hyperinsulinism.