However, although sporadic patients were somewhat more advanced, both in disease duration and in the FTD-CDR-SOB, C9orf72 mutation carriers showed significantly smaller volumes of the sensory, premotor, posterior parietal, occipital, temporal and prefrontal subregion of the thalamus (Figure 2 and Table 2). The gene discussed is C9orf72; the disease is frontotemporal dementia.