CD8A and cancer: This analysis documented that in tissues surrounding HCC, immune cell subsets required for an effective cytotoxic anti-cancer response such as T cells, CD8+ T cells, cytotoxic cells (representing CD8+ T cells, Tγδ and NK cells), Th1 cells, Tγδ cells and APCs were highly increased (Fig. 2A, HCC-NT vs. HL).