In terms of what type of gene was particularly affected by chronic DNMT1 KD, the enrichment analyses and laboratory verification consistently pointed at the same small group of gene categories, namely (1)neuroepithelial genes, and in particular the protocadherins; (2) fat homoeostasis/body mass genes; (3) olfactory receptors; (4) the cancer/testis antigens; and (5) the UGT1A complex. Here, PCDH11X is linked to cancer.