CX3CL1 treatment restored the decreased gamma amino butyric acid (GABA)-evoked currents in excitatory neurons recorded in fresh cortical slices resected from patients with temporal lobe epilepsy, which implies that CX3CL1 promotes the stability of GABA-evoked currents and thereby regulates the excitatory/inhibitory (E/I) balance of neural circuits [51]. The gene discussed is CX3CL1; the disease is temporal lobe epilepsy.