Multivariate logistic regression analysis, which included variables with p < 0.10 in the univariate analysis (severe OSA and elevated NBL1-Ab levels), demonstrated an independent association of only elevated NBL1-Ab level with CAD (OR: 6.75, 95% CI: 1.63–34.9, p = 0.008). Here, NBL1 is linked to obstructive sleep apnea syndrome.